| Bioactivity | S-Gboxin, a functional analogue of Gboxin, inhibits growth of mouse and human glioblastoma (GBM) with an IC50 of 470 nM[1]. Antitumour activity[1]. |
| In Vivo | S-Gboxin retains excellent metabolic stability, enhanced plasma stability, and PK-properties suitable for in vivo studies. S-Gboxin (10 mg/kg/day; intraperitoneally) inhibits glioblastoma (GBM) growth in vivo[1]. Animal Model: |
| Name | S-Gboxin |
| CAS | 2101317-21-7 |
| Formula | C27H32F3IN2O2 |
| Molar Mass | 600.45 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Shi Y, et al. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Nature. 2019 Mar;567(7748):341-346. |
S-Gboxin
CAS: 2101317-21-7 F: C27H32F3IN2O2 W: 600.45
S-Gboxin, a functional analogue of Gboxin, inhibits growth of mouse and human glioblastoma (GBM) with an IC50 of 470 nM.
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