Bioactivity | S 1924 is a potent H+, K+-ATPase inhibitor, with IC50 values of 10.3 and 1.6 μM at pH 7.4 and pH 6.0, respectively[1]. |
Invitro | S 1924 抑制组胺 (HY-B1204) 和 dbc-AMP (HY-B0764) 刺激的 14C-aminopyrine 摄取[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> S 1924 相关抗体: |
In Vivo | S 1924 (0.5 mg/kg,静脉注射)可抑制去谷泌胃素 (100 μg/kg/h,静脉注射)刺激的胃腔灌注大鼠中胃酸分泌[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
CAS | 111371-30-3 |
Formula | C12H11N3OS2 |
Molar Mass | 277.37 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Herling AW, et al. A substituted thieno[3.4-d]imidazole versus substituted benzimidazoles as H+, K+-ATPase inhibitors. Pharmacology. 1988;36(5):289-97. |