| Bioactivity | Rubitecan (RFS 2000), a Camptothecin derivative, is an orally active topoisomerase I inhibitor with broad antitumor activity, and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells[1][2][3]. | ||||||||||||
| Invitro | Rubitecan (RFS 2000) inhibits U-CH1, U-CH2, and CCL4 cells with IC50s 0.32, 0.83, and 7.7 µM, respectively[4]. | ||||||||||||
| Name | Rubitecan | ||||||||||||
| CAS | 91421-42-0 | ||||||||||||
| Formula | C20H15N3O6 | ||||||||||||
| Molar Mass | 393.35 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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