| Bioactivity | Rosmanol could inhibit the oxidation of low density lipoprotein (LPL) and significantly inhibit lipopolysaccharide induced iNOS and COX-2 expression, with anti-inflammatory effect. | ||||||||||||
| Invitro | Rosmanol exhibits the strongest inhibition on cell viability with IC50 approximately 42 μM. Rosmanol might suppress cancer cell proliferation or induce cancer cell undergoing apoptosis that lead to cell growth-inhibition. With 50 μM of Rosmanol treatment, the percentage of COLO 205 cells undergoing apoptosis increase dramatically from 9 h (29%) to 24 h (51%). Within 24 h of treatment with 50 μM Rosmanol, COLO 205 cells exhibit significant morphological changes and chromosomal condensation, which is indicative of apoptotic cell death[1]. Carnosol is a lipid protector against attack by O2[2]. | ||||||||||||
| Name | Rosmanol | ||||||||||||
| CAS | 80225-53-2 | ||||||||||||
| Formula | C20H26O5 | ||||||||||||
| Molar Mass | 346.42 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Rosmanol
CAS: 80225-53-2 F: C20H26O5 W: 346.42
Rosmanol could inhibit the oxidation of low density lipoprotein (LPL) and significantly inhibit lipopolysaccharide induc
Data collection：peptidedb@qq.com
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