Bioactivity | Romazarit (RO 31-3948) is an anti-inflammatory agent with antirheumatic effect. Romazarit (30 mg/kg) inhibits the development of hindpaw inflammation in an adjuvant arthritis model[1][2]. |
CAS | 109543-76-2 |
Formula | C15H16ClNO4 |
Molar Mass | 309.74 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bloxham DP, et al. Biologic properties of romazarit (Ro 31-3948), a potential disease-modifying antirheumatic drug. J Pharmacol Exp Ther. 1990 Mar;252(3):1331-40. [2]. Pillai AD, et al. Tetra substituted thiophenes as anti-inflammatory agents: exploitation of analogue-based drug design. Bioorg Med Chem. 2005 Dec 15;13(24):6685-92. |