PeptideDB

Ro 18-5364

CAS: 101387-98-8 F: C22H25N3O3S W: 411.52

Ro 18-5364 is an inhibitor of gastric (H? + K?)-ATPase, which has the effect of inhibiting the activity of the enzyme. R
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Bioactivity Ro 18-5364 is an inhibitor of gastric (H? + K?)-ATPase, which has the effect of inhibiting the activity of the enzyme. Ro 18-5364 has a very strong inhibitory effect on gastric mucosal (H? + K?)-ATPase, and the inhibitory effect is more significant at low pH. At the same time, there is no selectivity difference between the two enantiomers of (H? + K?)-ATPase, and its inhibitory effect can be studied and verified by a variety of experimental methods, including inhibition of enzyme activity, proton transport, and studies on its binding.
CAS 101387-98-8
Formula C22H25N3O3S
Molar Mass 411.52
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Ro 18-5364, a potent new inhibitor of the gastric (H+ + K+)-ATPase [2]. Multimilligram enantioresolution of sulfoxide proton pump inhibitors by liquid chromatography on polysaccharide-based chiral stationary phase