| Bioactivity | Ro 14-9578 is a tricyclic quinolone analog with antibacterial activity. Ro 14-9578 inhibits DNA biosynthesis (IC50=117 μM) and DNA supercoiling (IC50=66.8 μM) in Escherichia coli. Furthermore, Ro 14-9578 exhibits inhibitory effects against various Gram-negative bacteria and Staphylococcus aureus[1]. |
| CAS | 100891-41-6 |
| Formula | C16H13NO5 |
| Molar Mass | 299.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Georgopapadakou N H, et al. Monocyclic and tricyclic analogs of quinolones: mechanism of action[J]. Antimicrobial agents and chemotherapy, 1987, 31(4): 614-616. |