Bioactivity | Rizedisben (GE3126) is a fluorophore that can be used in fluorescence image-guided surgery. Rizedisben reduces non-specific adipose tissue fluorescence intensity and enhances nerve visibility[1]. |
In Vivo | Rizedisben(GE3126)(i.v., 1.6-46.6 mg/kg, a single dose)使小鼠坐骨神经的荧光发射强度呈剂量依赖性增加,当剂量增加到 16.6 mg/kg 以上时,神经荧光的增加变得更加温和,且随着 GE3126 浓度的增加,脂肪组织中信号饱和较慢,而相邻肌肉组织中荧光极少[1]。 |
Name | Rizedisben |
CAS | 1311570-07-6 |
Formula | C29H33N3O4S |
Molar Mass | 519.66 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Victoria E Cotero, et al. Improved Intraoperative Visualization of Nerves through a Myelin-Binding Fluorophore and Dual-Mode Laparoscopic Imaging. PLoS One. 2015 Jun 15;10(6):e0130276. |