| Bioactivity | Ritolukast (Wy-48252) is an orally active aerosol leukotriene (LTD4/E4) receptor antagonist. Ritolukast can be used to inhibit the bronchoconstriction caused by aerosol LTD4 in guinea pigs, with an ID50 of 0.5mg/kg[1]. |
| Name | Ritolukast |
| CAS | 111974-60-8 |
| Formula | C17H13F3N2O3S |
| Molar Mass | 382.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hand JM, etal. Prevention and reversal of aerosol LTD4-induced changes in guinea pigpulmonary mechanics by Wy-48252, an orally active LTD4/E4 receptor antagonist.Int Arch Allergy Appl Immunol. 1989;89(1):78-82. |
Ritolukast
CAS: 111974-60-8 F: C17H13F3N2O3S W: 382.36
Ritolukast (Wy-48252) is an orally active aerosol leukotriene (LTD4/E4) receptor antagonist. Ritolukast can be used to i
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