Bioactivity | Ritlecitinib tosylate is an orally active and selective?JAK3?inhibitor with an?IC50?of 33.1 nM. Ritlecitinib tosylate is used for inflammatory and autoimmune diseases research[1]. |
Name | Ritlecitinib tosylate |
CAS | 2192215-81-7 |
Formula | C22H27N5O4S |
Molar Mass | 457.55 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Telliez JB, et al. Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition. ACS Chem Biol. 2016 Dec 16;11(12):3442-3451. |