| Bioactivity | Rifapentine (DL 473) is an antibiotic compound used in the treatment of tuberculosis.Target: AntibacterialRifapentine inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme. A review of alternative regimens for prevention of active tuberculosis in HIV-negative individuals with latent TB found that a weekly, directly observed regimen of rifapentine with isoniazid for three months was as effective as a daily, self -administered regimen of isoniazid for nine months. But the rifapentine-isoniazid regimen had higher rates of treatment completion and lower rates of hepatotoxicity . However the rates of treatment-limiting adverse events were higher in the rifapentine-isoniazid regimen [1]. | ||||||||||||
| Name | Rifapentine | ||||||||||||
| CAS | 61379-65-5 | ||||||||||||
| Formula | C47H64N4O12 | ||||||||||||
| Molar Mass | 877.03 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Rifapentine
CAS: 61379-65-5 F: C47H64N4O12 W: 877.03
Rifapentine (DL 473) is an antibiotic compound used in the treatment of tuberculosis.Target: AntibacterialRifapentine in
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