| Bioactivity | Ricinelaidic acid,a 12-hydroxy fatty acid，is a leukotriene B4 (LTB4) receptor antagonist with the Ki of 2 µM in porcine neutrophil membranes. Ricinelaidic acid inhibits chemotaxis and calcium flux induced by LTB4 in isolated human neutrophils (IC50values = 10 and 7 µM, respectively). Ricinelaidic acid inhibits bronchoconstriction induced by LTB4 in rats[1]. |
| CAS | 540-12-5 |
| Formula | C18H34O3 |
| Molar Mass | 298.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yagaloff KA, et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids. 1995;52(5):293-297. |
Ricinelaidic acid
CAS: 540-12-5 F: C18H34O3 W: 298.46
Ricinelaidic acid,a 12-hydroxy fatty acid，is a leukotriene B4 (LTB4) receptor antagonist with the Ki of 2 µM in porcin
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