| Bioactivity | Reversin 121 is a P-glycoprotein inhibitor. Reversin 121 increases the ATPase activity of MDR1. Reversin 121 reverses P-glycoprotein-mediated multidrug resistance. Reversin 121 can be used in the research of cancers[1][2]. |
| Invitro | Reversin 121 (12 μg/mL) (with gemcitabine (HY-17026)) reduces the proportions of tumor cells positive for MDR proteins in Panc1 cell[1].Reversin 121 (5 μM) reverses the resistance against paclitaxel in paclitaxel-resistant NCI-H460 cell[2].Reversin 121 (10 μM, 48 h) inhibits T cell proliferation[3]. |
| Name | Reversin 121 |
| CAS | 174630-04-7 |
| Formula | C34H47N3O9 |
| Molar Mass | 641.75 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reversin 121
CAS: 174630-04-7 F: C34H47N3O9 W: 641.75
Reversin 121 is a P-glycoprotein inhibitor. Reversin 121 increases the ATPase activity of MDR1. Reversin 121 reverses P-
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