| Bioactivity | Retrorsine is a naturally occurring toxic pyrrolizidine alkaloid. Retrorsine can bind with DNA and inhibits the proliferative capacity of hepatocytes. Retrorsine can be used for the research of hepatocellular injury[1][2]. |
| Invitro | Retrorsine (60-240 μM; 24 hours) significantly reduces HSEC-CYP3A4 cells viability and GSH levels, and increases formation of pyrrole-protein adducts[3]. Cell Viability Assay[3] Cell Line: |
| Name | Retrorsine |
| CAS | 480-54-6 |
| Formula | C18H25NO6 |
| Molar Mass | 351.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
Retrorsine
CAS: 480-54-6 F: C18H25NO6 W: 351.39
Retrorsine is a naturally occurring toxic pyrrolizidine alkaloid. Retrorsine can bind with DNA and inhibits the prolifer
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