| Bioactivity | Retro-2 cycl (RN 1-001) is a dihydroquinazolinone (DHQZ) inhibitor of retrograde trafficking. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus with IC50s of 54 μM and 160 μM, respectively[1]. Antiviral agent[1]. | ||||||||||||
| Name | Retro-2 cycl | ||||||||||||
| CAS | 1429192-00-6 | ||||||||||||
| Formula | C19H16N2OS | ||||||||||||
| Molar Mass | 320.41 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Carney DW, et al. Structural optimization of a retrograde trafficking inhibitor that protects cells from infections by human polyoma- and papillomaviruses. Bioorg Med Chem. 2014 Sep 1;22(17):4836-47. |
Retro-2 cycl
CAS: 1429192-00-6 F: C19H16N2OS W: 320.41
Retro-2 cycl (RN 1-001) is a dihydroquinazolinone (DHQZ) inhibitor of retrograde trafficking. Retro-2 cycl (RN 1-001) in
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