| Bioactivity | Retinestatin, a new polyol polyketide, can protect SH-SY5Y dopaminergic cells from MPP+ (HY-W008719)-induced cytotoxicity. Retinestatin shows neuroprotective effects in an in vitro model of Parkinson’s disease[1]. |
| Invitro | Retinestatin (10 μM；预处理 24 小时) 显着减弱 MPP+ (2 mM；24 小时) 诱导的 SH-SY5Y 多巴胺能神经元细胞毒性[1]。Retinestatin (10 μM；预处理 24 小时) 可挽救 MPP+ 诱导的 Bcl-xL 表达下调和 Bak 表达上调[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Retinestatin 相关抗体: Cell Cytotoxicity Assay[1] Cell Line: |
| Formula | C25H40O12 |
| Molar Mass | 532.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Thanh-Hau Huynh, et al. Retinestatin, a Polyol Polyketide from a Termite Nest-Derived Streptomyces sp. J Nat Prod. 2024 Mar 5. |