Bioactivity | Resolvin D1 methyl ester (RvD1 methyl ester) is the methyl ester of Resolvin D1 (HY-125527). Resolvin D1 methyl ester reduces triglyceride levels[1]. |
In Vivo | Treating diabetic mice with menhaden oil in the diet or exogenously with resolvins D1 and E1 or the methyl esters of resolvins D1 (1 ng/g ; i.p.; daily) and D2 reduced triglyceride levels to control values or lower in type 2 diabetes C57BL/6J mice[1]. Treating diabetic mice with the methyl esters of resolvins D1 or D2 significantly improved motor nerve conduction velocity compared to non-treated diabetic mice but both motor and sensory nerve conduction velocities in these treated mice remained significantly impaired compared to control mice[1]. |
Name | Resolvin D1 methyl ester |
CAS | 937738-63-1 |
Formula | C23H34O5 |
Molar Mass | 390.51 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Alexander Obrosov, et al. Effect of Fish Oil vs. Resolvin D1, E1, Methyl Esters of Resolvins D1 or D2 on Diabetic Peripheral Neuropathy. J Neurol Neurophysiol. 2017;8(6):453. |