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Regorafenib N-oxide and N-desmethyl (M5)-d3

CAS: F: C20H10D3ClF4N4O4 W: 487.81

Regorafenib N-oxide and N-desmethyl (M5)-d3 is deuterium labeled Regorafenib N-oxide and N-desmethyl (M5).
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Regorafenib N-oxide and N-desmethyl (M5)-d3 is deuterium labeled Regorafenib N-oxide and N-desmethyl (M5).
Invitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name Regorafenib N-oxide and N-desmethyl (M5)-d3
Formula C20H10D3ClF4N4O4
Molar Mass 487.81
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.