| Bioactivity | Regorafenib N-oxide and N-desmethyl (M5)-13C6 is the 13C-labeled Regorafenib N-oxide and N-desmethyl (M5)[1]. | ||||||||||||
| Invitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. | ||||||||||||
| Name | Regorafenib N-oxide and N-desmethyl (M5)-13C6 | ||||||||||||
| Formula | C1413C6H13ClF4N4O4 | ||||||||||||
| Molar Mass | 490.74 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. |
Regorafenib N-oxide and N-desmethyl (M5)-13C6
CAS: F: C1413C6H13ClF4N4O4 W: 490.74
Regorafenib N-oxide and N-desmethyl (M5)-13C6 is the 13C-labeled Regorafenib N-oxide and N-desmethyl (M5).
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