| Bioactivity | Recainam (Wy-42362) is an orally active anti-arrhythmic agent with Class I electrophysiological properties. Recainam suppresses complex ventricular arrhythmias. Racainam exhibits a good pharmacokinetic character in Sprague Dawley rats[1][2]. | |||||||||
| In Vivo | Racainam (20 mg/kg，静脉注射) 表现出良好的药代动力学特征，AUC0-inf 为 4.1 μg·h/mL，半衰期 T1/2 为 0.6 h，MRT 为 0.6 h，清除率为 4.9 L/kg·h，分布容积 Vss 为 3.2 L/kg[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. | |||||||||
| CAS | 74738-24-2 | |||||||||
| Formula | C15H25N3O | |||||||||
| Molar Mass | 263.38 | |||||||||
| Appearance | 固体 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Scatina JA, et al., Species differences in the pharmacokinetics of recainam, a new anti-arrhythmic drug. Biopharm Drug Dispos. 1990 Jul;11(5):445-61. [2]. Anastasiou-Nana MI, et al., Recainam, a potent new antiarrhythmic agent: effects on complex ventricular arrhythmias. J Am Coll Cardiol. 1986 Aug;8(2):427-35. |