Bioactivity | Recainam (Wy-42362) hydrochloride is an orally active anti-arrhythmic agent with Class I electrophysiological properties. Recainam suppresses complex ventricular arrhythmias. Racainam hydrochloride exhibits a good pharmacokinetic character in Sprague Dawley rats[1][2]. |
In Vivo | Racainam hydrochloride (20 mg/kg,静脉注射) 表现出良好的药代动力学特征,AUC0-inf 为 4.1 μg·h/mL,半衰期 T1/2 为 0.6 h,MRT 为 0.6 h,清除率为 4.9 L/kg·h,分布容积 Vss 为 3.2 L/kg[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
CAS | 74752-07-1 |
Formula | C15H26ClN3O |
Molar Mass | 299.84 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Scatina JA, et al., Species differences in the pharmacokinetics of recainam, a new anti-arrhythmic drug. Biopharm Drug Dispos. 1990 Jul;11(5):445-61. [2]. Anastasiou-Nana MI, et al., Recainam, a potent new antiarrhythmic agent: effects on complex ventricular arrhythmias. J Am Coll Cardiol. 1986 Aug;8(2):427-35. |