| Bioactivity | RdRP-IN-8 (compound 45) is an anti-influenza virus compound. RdRP-IN-8 inhibits viral RNA-dependent RNA polymerase (RdRP) activity by disrupting heterodimerization of PA and PB1 subunits (EC50=0.13 μM)[1]. |
| Formula | C23H21N3O6S |
| Molar Mass | 467.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bonomini, et al. "Optimization of Potent, Broad-spectrum, and Specific Anti-influenza Compounds Targeting RNA Polymerase PA-PB1 heterodimerization." European Journal of Medicinal Chemistry (2024): 116737. |