| Bioactivity | RXFP3/4 agonist 1 is an agonist of relaxin family peptide 3/4 receptor (RXFP3/4), with EC50s of 82/2 nM, respectivley. RXFP3/4 agonist 1 increases food intake in rats[1]. |
| Target | EC50: 82 nM (RXFP3), 2 nM (RXFP4) |
| Invitro | RXFP3/4 agonist 1 (Compound 4) inhibits orskolin-stimulated cAMP accumulation in CHO-K1 cells stably overexpressing RXFP3 and RXFP4, with EC50s of 12.8 and 1.6 nM, respectively[1]. |
| Name | RXFP3/4 agonist 1 |
| CAS | 2351104-40-8 |
| Formula | C20H22ClN5O |
| Molar Mass | 383.87 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. DeChristopher B, et al. Discovery of a small molecule RXFP3/4 agonist that increases food intake in rats upon acute central administration. Bioorg Med Chem Lett. 2019 Apr 15;29(8):991-994. |
RXFP3/4 agonist 1
CAS: 2351104-40-8 F: C20H22ClN5O W: 383.87
RXFP3/4 agonist 1 is an agonist of relaxin family peptide 3/4 receptor (RXFP3/4), with EC50s of 82/2 nM, respectivley. R
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