| Bioactivity | RWJ-445167 (3DP-10017) is a dual inhibitor of thrombin and factor Xa with Ki of 4.0 nM and 230 nM, respectively, exhibiting potent antithrombotic activity. |
| Target | Ki: 4.0 nM (thrombin), 230 nM (factor Xa) |
| Name | RWJ-445167 |
| CAS | 226566-43-4 |
| Formula | C18H24N6O5S |
| Molar Mass | 436.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. RWJ-445167, et al. Exploration of potential prodrugs of RWJ-445167, an oxyguanidine-based dual inhibitor of thrombin and factor Xa. Chem Biol Drug Des. 2006 Jul;68(1):29-36. |