| Bioactivity | RW3 is a small cationic hexapeptide with amphiphilic properties. RW3 targets the plasma membrane of bacteria and works by inhibiting cell respiration and cell wall synthesis. RW3 shows high biological activity against gram-positive bacteria and does not show significant cytotoxic or hemolytic effects in previous studies. RW3 quickly kills 97% of the initial colony forming units (CFU) within 10 minutes at twice the minimum inhibitory concentration (MIC). RW3 can be used in antimicrobial and antifungal studies[1]. |
| CAS | 359632-11-4 |
| Sequence | Arg-Trp-Arg-Trp-Arg-Trp-NH2 |
| Shortening | RWRWRW-NH2 |
| Formula | C51H69N19O6 |
| Molar Mass | 1044.22 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wenzel M, et al. Towards profiles of resistance development and toxicity for the small cationic hexapeptide RWRWRW-NH2[J]. Frontiers in Cell and Developmental Biology, 2016, 4: 86. |