RU 58642_product_DataBase

Bioactivity	RU 58642 is an orally active non-steroidal antiandrogen, which displays a strong and selective affinity for androgen receptor[1].
In Vivo	在体内，通过口服和皮下途径，在补充了丙酸睾酮的阉割大鼠和完整动物中评估了 RU-58642 对前列腺、精囊重量和血清睾酮水平的抗雄激素活性。在大鼠中，无论采用何种给药途径，RU 58642 在低至 0.3 mg/kg 的剂量下都能显著降低前列腺重量。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.
CAS	143782-63-2
Formula	C15H11F3N4O2
Molar Mass	336.27
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. T Battmann, et al. Pharmacological profile of RU 58642, a potent systemic antiandrogen for the treatment of androgen-dependent disorders. J Steroid Biochem Mol Biol. 1998 Jan;64(1-2):103-11.

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