| Bioactivity | RTC14 is a read-through compound (RTC) that can induce ribosomes to read through nonsense mutations in mRNA and allow the production of full-length functional proteins. RTC14 has the potential to be used in the research of many genetic disorders, such as nonsense mutations in the ATM and dystrophin genes[1]. |
| CAS | 414909-09-4 |
| Formula | C17H18N2O3 |
| Molar Mass | 298.34 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kayali R, et al. Read-through compound 13 restores dystrophin expression and improves muscle function in the mdx mouse model for Duchenne muscular dystrophy. Hum Mol Genet. 2012 Sep 15;21(18):4007-20. |