Bioactivity | RSV-IN-4 (Compound 2) is a dual inhibitor of respiratory syncytial virus (RSV) and influenza virus A (IAV). RSV-IN-4 shows anti-RSV activity (EC50 = 11.76 μM)[1]. |
Invitro | RSV-IN-4 (compound 2) (50 µM)shows the inhibition of 83.24% for RSV in a fluorescence-based assay with little or no toxicity to HEp-2 cells[1]. |
Name | RSV-IN-4 |
CAS | 862825-89-6 |
Formula | C18H18N2O2S |
Molar Mass | 326.41 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Guo-Ning Zhang, et al. Design and synthesis of 2-((1H-indol-3-yl)thio)-N-phenyl-acetamides as novel dual inhibitors of respiratory syncytial virus and influenza virus A. Eur J Med Chem. 2020 Jan 15;186:111861. |