| Bioactivity | RSC133 exhibits dual activity by inhibiting histone deacetylase and DNA methyltransferase. RSC133 effectively facilitates reprogramming of human somatic cells to pluripotent stem cells and supports the maintenance of an undifferentiated state of human pluripotent stem cells[1]. | |||||||||
| Name | RSC133 | |||||||||
| CAS | 1418131-46-0 | |||||||||
| Formula | C18H15N3O2 | |||||||||
| Molar Mass | 305.33 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Lee J, et al. A novel small molecule facilitates the reprogramming of human somatic cells into a pluripotent state and supports the maintenance of an undifferentiated state of human pluripotent stem cells. Angew Chem Int Ed Engl. 2012 Dec 7;51(50):12509-1 |