| Bioactivity | RS 49676 is an N-substituted imidazole compound that exhibits strong in vitro activity against endogenous amoebae (ED50 < 0.1 ng/mL), but is ineffective against exogenous amoebae (epimastigotes). In vivo, RS 49676 (100 mg/kg/d, sc, 2 times) can prolong the average survival time of mice infected with Trypanosoma cruzi to more than 11 weeks. |
| CAS | 111962-89-1 |
| Formula | C25H28ClN3O5 |
| Molar Mass | 485.96 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. The efficacy of an N-substituted imidazole, RS-49676, against a Trypanosoma cruzi infection in mice. |
RS 49676
CAS: 111962-89-1 F: C25H28ClN3O5 W: 485.96
RS 49676 is an N-substituted imidazole compound that exhibits strong in vitro activity against endogenous amoebae (ED50
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