| Bioactivity | RR-11055 (Compound 8) is a ligand for E3 ligase, that exhibits an affinity with cereblon with Ki of 0.38 μM. RR-11055 can be used for synthesis of PROTAC Degrader ERD-1233 (HY-169367)[1]. |
| CAS | 3026009-09-3 |
| Formula | C18H20N4O4 |
| Molar Mass | 356.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Acharyya RK, et al., Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer. J Med Chem. 2024 Nov 14;67(21):19010-19037. |