Bioactivity | RPR-106541 is a 17-thiosteroid. RPR 106541 has potent glucocorticosteroid activity. RPR 106541 also has demonstrable effects on carbohydrate and lipid metabolism[1]. |
In Vivo | RPR-106541 可显著抑制肺内 CD4+ T 细胞积聚和嗜酸性粒细胞积聚,同时抑制实验性大鼠肺部炎症模型中白细胞介素 (IL)-4 和 IL-5 的 mRNA 表达[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
CAS | 159001-35-1 |
Formula | C24H34F2O4S |
Molar Mass | 456.59 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Miller GK, et al. Chronic effects of the novel glucocorticosteroid RPR 106541 administered to beagle dogs by inhalation. Toxicol Pathol. 2000 Mar-Apr;28(2):226-36. |