Bioactivity | RP-182-PEG3-K palmitic acid (Compound 1a) inhibits CD206high M2-like macrophage (IC50 of 3.2 µM) and induces phagocytosis. RP-182-PEG3-K palmitic acid exhibits antitumor efficacy in mouse B16 melanoma allografts[1]. |
Formula | C99H161N23O16 |
Molar Mass | 1929.48 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Singh SS, et al., Fatty acid derivatization and cyclization of the immunomodulatory peptide RP-182 targeting CD206high macrophages improves anti-tumor activity. Mol Cancer Ther. 2024 Aug 30. |