Bioactivity | RORγt agonist 2 is a potent agonist of RORγt. RORγt agonist 2 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 2 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136339A1, compound 17)[1]. |
Name | RORγt agonist 2 |
CAS | 2663787-92-4 |
Formula | C30H30F3N3O4S |
Molar Mass | 585.64 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Liu Bin, et al. Amides with bicyclic structures and their applications in pharmaceuticals. Patent WO2021136339A1. |