PeptideDB

RORγ/DHODH-IN-2

CAS: 3000567-45-0 F: C22H16D2ClF4N5O2 W: 497.87

RORγ/DHODH-IN-2 (Compound 1311) is an orally active dual inhibitor of RORγ/DHODH with IC50 values of 11.9 nM and 90 nM
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Bioactivity RORγ/DHODH-IN-2 (Compound 1311) is an orally active dual inhibitor of RORγ/DHODH with IC50 values of 11.9 nM and 90 nM, respectively. RORγ/DHODH-IN-2 exhibits antiviral activity by inhibiting the activity of SARS-CoV-2, HCMV, HAdV5, and MPXV, with IC50 values of 27 nM, 20 nM, 9.1 nM, and 1.8 nM, respectively[1].
Target IC50: 11.9 nM (RORγ). IC50: 90 nM (DHODH).
CAS 3000567-45-0
Formula C22H16D2ClF4N5O2
Molar Mass 497.87
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.