| Bioactivity | RORγ/DHODH-IN-1 (compound 1404), a deuterium labeled compound, is a dual RORγ and DHODH inhibitor with IC50 values of 9.7 nM and 100 nM, repaectively. RORγ/DHODH-IN-1 blocks the replication of SARS-CoV-2, HCMV, and non-enveloped DNA virus (HAdV5)[1]. |
| CAS | 3000567-76-7 |
| Formula | C23H13D2Cl2F4N3O2 |
| Molar Mass | 514.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Alexandra Herrmann, et al. Orally bioavailable RORγ/DHODH dual host-targeting small molecules with broad-spectrum antiviral activity. Antiviral Res. 2024 Sep 19:231:106008. |
RORγ/DHODH-IN-1
CAS: 3000567-76-7 F: C23H13D2Cl2F4N3O2 W: 514.30
RORγ/DHODH-IN-1 (compound 1404), a deuterium labeled compound, is a dual RORγ and DHODH inhibitor with IC50 values of
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