RORγ allosteric probe-1_product_DataBase

CAS: 2983890-50-0 F: C50H37ClF3N5O11S W: 1008.37

RORγ allosteric probe-1 (Compound 12h) is a RORγ allosteric fluorescent probe (Ex/Em: 490/524 nm). RORγ allosteric pr

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	RORγ allosteric probe-1 (Compound 12h) is a RORγ allosteric fluorescent probe (Ex/Em: 490/524 nm). RORγ allosteric probe-1 can be used for exploration of RORγ allosteric inhibitors and RORγ function[1].
In Vivo	RORγ allosteric probe-1 (1 μM，与斑马鱼一起孵育，12 小时) 在绿色通道下的肝脏和肠道中显示荧光，这与报道的 RORγ 表达谱一致[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.
CAS	2983890-50-0
Formula	C50H37ClF3N5O11S
Molar Mass	1008.37
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Yu YC, et al. Discovery of RORγ Allosteric Fluorescent Probes and Their Application: Fluorescence Polarization, Screening, and Bioimaging. J Med Chem. 2024 Mar 14;67(5):4194-4224.

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