| Bioactivity | RORγ-IN-2 (Compound 22) is a RORγ inhibitor, with a Ki of 16.6 nM for hRORγ. RORγ-IN-2 can be used for the research of IL-17-dependent autoimmune diseases[1]. |
| CAS | 2088333-58-6 |
| Formula | C28H32F3N5O4S2 |
| Molar Mass | 623.71 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lugar CW, et al. Defining Target Engagement Required for Efficacy In Vivo at the Retinoic Acid Receptor-Related Orphan Receptor C2 (RORγt). J Med Chem. 2021 May 13;64(9):5470-5484. |
RORγ-IN-2
CAS: 2088333-58-6 F: C28H32F3N5O4S2 W: 623.71
RORγ-IN-2 (Compound 22) is a RORγ inhibitor, with a Ki of 16.6 nM for hRORγ. RORγ-IN-2 can be used for the research
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