| Bioactivity | ROCK2-IN-9 (compound 7u) is a selective ROCK2 inhibitor (IC50=36.8 nM) with anticancer activity. ROCK2-IN-9 inhibits cancer cell migration and invasion by regulating multiple cellular activities of the actin cytoskeleton. ROCK2-IN-9 can be used in breast cancer research[1]. |
| Formula | C28H30N8O2 |
| Molar Mass | 510.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhi Cao, et al. "Discovery of novel pyrazolo [1, 5-a] pyrimidine derivatives as selective ROCK2 inhibitors with anti-breast cancer migration and invasion activities." Bioorganic Chemistry (2024): 107675. |