Bioactivity | ROCK inhibitor-2 is a selective dual ROCK1 and ROCK2 inhibitor with IC50s of 17 nM and 2 nM, respectively[1]. | ||||||||||||
Name | ROCK inhibitor-2 | ||||||||||||
CAS | 1127308-52-4 | ||||||||||||
Formula | C21H20N2O2 | ||||||||||||
Molar Mass | 332.40 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Hobson AD, et al. Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based DrugDesign. J Med Chem. 2018 Dec 27;61(24):11074-11100. |