| Bioactivity | ROCK-IN-9 (Compound T345) is a ROCK inhibitor. ROCK-IN-9 shows cytotoxicity in HepG2 cell, with an IC50 of 40.8 μM. ROCK-IN-9 has good pharmacokinetic properties in mice, and shows high in vivo exposure and oral bioavailability at lower doses[1]. |
| Name | ROCK-IN-9 |
| CAS | 2643334-76-1 |
| Formula | C20H20FN5O2 |
| Molar Mass | 381.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li, Jinping, et al. Rock inhibitor, preparation method therefor and use thereof. WO2021093795. |
ROCK-IN-9
CAS: 2643334-76-1 F: C20H20FN5O2 W: 381.40
ROCK-IN-9 (Compound T345) is a ROCK inhibitor. ROCK-IN-9 shows cytotoxicity in HepG2 cell, with an IC50 of 40.8 μM. ROC
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