| Bioactivity | ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2. | ||||||||||||
| Invitro | ROCK-IN-1 shows potent cellular efficacy, with an EC50 of 200 nM[1]. | ||||||||||||
| Name | ROCK-IN-1 | ||||||||||||
| CAS | 934387-35-6 | ||||||||||||
| Formula | C20H18FN3O | ||||||||||||
| Molar Mass | 335.37 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Boland S, et al. 3-[2-(Aminomethyl)-5-[(pyridin-4-yl)carbamoyl]phenyl] benzoates as soft ROCK inhibitors. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6442-6. |