| Bioactivity | RO5488608 is a negative allosteric metabotropic modulator of glutamate receptor 2/3. RO5488608 inhibits LY354740 (HY-18941)-induced intracellular Ca2+ release and can be used for study of antidepressant[1]. |
| CAS | 1337920-46-3 |
| Formula | C23H17F3N2O4S |
| Molar Mass | 474.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lundström L, et al. Structural determinants of allosteric antagonism at metabotropic glutamate receptor 2: mechanistic studies with new potent negative allosteric modulators. Br J Pharmacol. 2011;164(2b):521-537. |
RO5488608
CAS: 1337920-46-3 F: C23H17F3N2O4S W: 474.45
RO5488608 is a negative allosteric metabotropic modulator of glutamate receptor 2/3. RO5488608 inhibits LY354740 (HY-189
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