| Bioactivity | RO27-3225 TFA is potent and selective melanocortin 4 receptor (MC4R) agonist with an EC50 of 1 nM and 8 nM for MC4R and MC1R, respectively. RO27-3225 TFA shows ~30-fold selectivity for MC4R over MC3R. RO27-3225 TFA has neuroprotective and anti-inflammatory effects[1][2][3]. | ||||||
| Name | RO27-3225 TFA | ||||||
| Sequence | Oxobutyl-His-Phe-Arg-Trp-{Sar}-NH2 | ||||||
| Shortening | Oxobutyl-HFRW-{Sar}-NH2 | ||||||
| Formula | C41H53F3N12O8 | ||||||
| Molar Mass | 898.93 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |