| Bioactivity | RNA Aptamer Mango Ⅲ (sodium) has an exceptionally high affinity to TO1-biotin (a thiazole orange derivative fluorophore), and can be used to visualize RNA expression or localization in live cells. Compared to the original Mango I aptamer, RNA Aptamer Mango Ⅲ has markedly improved fluorescent properties, binding affinities, and salt dependencies. |
| Name | RNA Aptamer Mango Ⅲ sodium |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhong W, Sczepanski JT. A Mirror Image Fluorogenic Aptamer Sensor for Live-Cell Imaging of MicroRNAs. ACS Sens. 2019;4(3):566-570. doi:10.1021/acssensors.9b00252 [2]. Autour A, C Y Jeng S, D Cawte A, et al. Fluorogenic RNA Mango aptamers for imaging small non-coding RNAs in mammalian cells. Nat Commun. 2018;9(1):656. Published 2018 Feb 13. doi:10.1038/s41467-018-02993-8 |