| Bioactivity | RMS-07 is a covalent Monopolar Spindle Kinase 1 (MPS1/TTK) inhibitor, with an apparent IC50 of 13.1 nM. RMS-07 targets a poorly conserved cysteine in the kinase's hinge region[1]. |
| Target | IC50：13.1 nM （Monopolar Spindle Kinase 1 (MPS1/TTK)）. |
| Name | RMS-07 |
| CAS | 2645409-78-3 |
| Formula | C35H40N8O2 |
| Molar Mass | 604.74 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ricardo A M Serafim, et al. Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor. J Med Chem. 2022 Feb 24;65(4):3173-3192. |