| Bioactivity | RK-1441B is an anti-phage antibiotic produced by Streptomyces sp. RK-1441 and belongs to the pyrrolo[1,4]benzodiazepine class. RK-1441B has antiphage activity but no significant antimicrobial activity against a supersusceptible E. coli strain to an antitumor antibiotic. RK-1441B is inactive in vitro and may be converted to the active form in the host organism. Its fellow antibiotic RK-1441A can form an adduct with guanine residues in the DNA chain to exert resistance[1]. |
| CAS | 132138-94-4 |
| Formula | C13H14N2O5 |
| Molar Mass | 278.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. New Pyrrolobenzodiazepine Antibiotics, RK-1441A and B I. Biological Properties |