PeptideDB

RIPK-IN-4

CAS: 2141969-56-2 F: C18H21FN4O3S W: 392.45

RIPK-IN-4 is a potent and selective RIPK2 inhibitor with excellent oral bioavailability, and has an IC50 of 3 nM.
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Bioactivity RIPK-IN-4 is a potent and selective RIPK2 inhibitor with excellent oral bioavailability, and has an IC50 of 3 nM[1].
Target IC50: 3 nM (RIPK2)
Name RIPK-IN-4
CAS 2141969-56-2
Formula C18H21FN4O3S
Molar Mass 392.45
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. He X, et al. Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. ACS Med Chem Lett. 2017 Sep 27;8(10):1048-1053.