| Bioactivity | RHPS4 is a potent telomerase inhibitor (IC50 = 0.33 μM). RHPS4 is a DNA damage inducer[1][2]. |
| Invitro | RHPS4 could sensitize tumor cells to anticancer agents that act via disparate mechanisms[1].RHPS4 (0.5-1 μM, 15 days) induces a senescent-like growth arrest in MCF-7 cells[1].RHPS4 (1 μM, 4 days) induces phosphorylation of H2AX in transformed and tumor cells[2]. Cell Proliferation Assay[1] Cell Line: |
| Name | RHPS4 |
| CAS | 390362-78-4 |
| Formula | C23H20F2N2O4S |
| Molar Mass | 458.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |