| Bioactivity | RGD-4C is a arginine-glycine-aspartic acid peptide (ACDCRGDCFC) with integrin binding activity. The Arg-Gly-Asp (RGD) sequence serves as the primary integrin recognition site in extracellular matrix proteins, and peptides containing this sequence can mimic the recognition specificity of the matrix proteins. RGD-4C is a αv-integrin ligand, can conjugate with bioactive molecule to exert antitumor effects in animal models[1][2][3]. |
| Invitro | RGD-4C (2.5, 5, 10 μg/mL) inhibits BAE cell proliferation by synthetic form modified with endostatin-derived peptides[2]. |
| Name | RGD-4C |
| CAS | 332179-76-7 |
| Shortening | ACDCRGDCFCG(Disulfide bridge: Cys2-Cys10; Cys4-Cys8) |
| Formula | C42H60N14O16S4 |
| Molar Mass | 1145.27 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
RGD-4C
CAS: 332179-76-7 F: C42H60N14O16S4 W: 1145.27
RGD-4C is a arginine-glycine-aspartic acid peptide (ACDCRGDCFC) with integrin binding activity. The Arg-Gly-Asp (RGD) se
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